Duromine drug is prescribed for losing weight. Duromine is rather a short-term additive to diet and physical activity. The anti-obesity drug Duromine is usually administered for patients with body mass index (BMI) 30 kg/m² or more. Duromine drug can also be prescribed for the treatment of obesity to patients, who have BMI 25 kg/m² and more, if excess weight exceeds the risk of related diseases.
The other medicine Reductil is a serotonin and norepinephrine reuptake inhibitor. Usually Reductil is administered for the treatment of obesity, if patient did not manage to reduce weight by low-calorie diet and physical exercises. Reductil drug allows to reduce weight and maintain the achieved result for long time.
Duromine or Reductil mechanism of action
- Duromine mechanism of action
Duromine drug was made on the basis of active substance Phentermine. It is known that Phentermine can suppress appetite by acting on hypothalamus, resulting in weight loss. Besides that, Phentermine acts on dopaminergic and noradrenergic nervous systems, as well as the cardiovascular system. By affecting the cardiovascular nervous system, Phentermine increases the rate and strength of cardiac contractions. Thus patients, who suffer from cardiovascular disorders, should be careful when using Duromine for the weight loss.
- Reductil mechanism of action
The active substance in Reductil drug is Sibutramine hydrochloride. Sibutramine hydrochloride measures the level of serotonin and noradrenalin that help to regulate the consumption of food. As a result, for saturation patient needs less food than usually. It is recommended to take anti-obesity drug Reductil in combination with low-calorie diet and physical activity.
Pharmaceutical form of drugs for obesity treatment Duromine or Reductil
- Duromine pharmaceutical form
The weight loss drug Duromine is produced in capsules for oral use:
- Duromine 15mg
- Duromine 30mg
- Duromine 40mg
In addition to the active substance Phentermine, each Duromine capsule contains excipients: magnesium stearate, liquid paraffin, lactose, gelatin, iron oxide black and titanium dioxide.
- Reductil pharmaceutical form
The weight loss drug Reductil comes in capsules for oral use:
- Reductil 10mg
- Reductil 15mg
In addition to the active substance Sibutramine hydrochloride, Reductil weight loss drug also contains some inactive ingredients: cellulose-microcrystalline; magnesium stearate; silica collodial anhydrous; titanium dioxide; gelatine; dimethicone; shellac; lecithin; iron oxide black; propylene glycol; indigo carmine; sodium lauryl sulphate.
Duromine or Reductil manufacturers
Molecular formula of the active substance Phentermine (Duromine weight loss drug) was developed by one pharmaceutical company TG United Labs. The FDA approved Phentermine under the trade name Phentermine Hydrochloride for the weight loss in March 14, 1977. The weight loss drug Phentermine is available on the global market under the following trade names:
- Adipex; Duromine; Fastin; Obestin; Oby-Trim; Ona-Mast; Suprenza; Tora; Wilpo, etc.
The molecular formula of the active substance Sibutramine hydrochloride (Reductil weight loss drug) was developed by the pharmaceutical company Abbott Laboratories Ltd. Later, on November 22, 1997, the FDA approved Sibutramine hydrochloride for the treatment of obesity. The drug was approved under the name Meridia. However, Sibutramine hydrochloride can be also bought under some other trade names:
- Ectiva; Reductil; Zytrim; Reduxade; Meridia, etc.
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